Take Tablets for Chronic and Severe Neuropathic pain. GABAPENTIN FDA approved for postherpetic neuralgia No significant drug interactons Limited intestinal absorption and well tolerated Decreases pain by modulating calciumum channel activity of the nerve cells NORTRIPTYLINE Increases levels Of serotonin and norepinephrine Improvements in insomnia, anxiety, depression Second generation tricyclic anti depressant which increases the levels of chemical messengers that stop the movement of pain signals in the brain